Weight-loss research peptide

GLP3-R

Three pathways.
One compound.

24.2%mean weight reduction in Phase 2*

GLP3-R is retatrutide — the triple-agonist studied for weight loss at the GLP-1, GIP and glucagon receptors.

Buy Now — 10MG10 mg · $142.99 · Purple Peptides
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Purple Peptides GLP3-R 10MG vial
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*Phase 2 trial published in NEJM, 2023. Illustrative image. Research use only. Not for human consumption.

Why GLP3-R?

Weight-loss research.
A third pathway.

Semaglutide targets GLP-1. Tirzepatide adds GIP. Retatrutide goes further with glucagon-receptor activity, opening a different direction in appetite, energy expenditure and body-weight research.

Buy Now — 10MG10 mg · $142.99 · Purple Peptides
Illustrative purple, blue and gold receptor protein structures
GLP-1

Appetite & glucose signaling

GIP

Insulin & metabolic regulation

Glucagon

Energy expenditure & hepatic function

Illustrative mountain landscape

Published weight-loss research

24.2% mean weight reduction.
One landmark Phase 2 trial.

In a 2023 study published in the New England Journal of Medicine, the highest-dose retatrutide group achieved a mean body-weight reduction of 24.2% at 48 weeks.

This was a controlled clinical trial using an investigational medicine, not Purple Peptides research vials. It does not establish results or safety for personal use.

  • Body-weight endpoints
  • Appetite signaling
  • Energy expenditure
  • Triple-receptor activity
  • Glucose regulation
  • Body-composition research
Buy Now — 10MG10 mg · $142.99 · Purple Peptides
Read the published study

Choose your research size

GLP3-R research vials

5MG

Research vial

$76.99

Purple Peptides GLP3-R 5MG vial
View 5MG option
  • Lab tested & verified
  • Batch COA available
  • Fast fulfillment
  • U.S. based support

30MG

Research vial

$241.99

Purple Peptides GLP3-R 30MG vial
View 30MG option
  • Lab tested & verified
  • Batch COA available
  • Fast fulfillment
  • U.S. based support
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How it works

Three receptors.
Multiple effects.

GLP3-R is designed to interact with GLP-1, GIP, and glucagon receptors. This multi-pathway activity is what makes it one of the most interesting compounds in modern research.

Buy Now — 10MG10 mg · $142.99 · Purple Peptides

Quality & transparency

Don't trust the label.
Check the data.

Make documentation part of your purchase. Review the product's batch-specific Certificate of Analysis for purity and identity testing before choosing your research vial.

Buy Now — 10MG10 mg · $142.99 · Purple Peptides
View batch COAs
Certificate of Analysis
Product
GLP3-R
Testing
Purity & identity
Documentation
Batch-specific report
View the original laboratory report

How it compares

A different research profile.

SemaglutideTirzepatideGLP3-R
GLP-1 receptor
GIP receptor
Glucagon receptor
Buy Now — 10MG10 mg · $142.99 · Purple Peptides

Frequently asked questions

Questions? We've got answers.

What is GLP3-R?

GLP3-R is retatrutide, an investigational peptide studied as an agonist at the GLP-1, GIP and glucagon receptors.

Where can I see the COA?

Certificates of Analysis are available on the Purple Peptides testing page. Check the certificate for the specific product and lot.

How is GLP3-R different from tirzepatide?

Tirzepatide targets GLP-1 and GIP. Retatrutide adds glucagon-receptor activity, which is studied for its effect on energy expenditure.

What size should I choose?

Select the research quantity appropriate for your laboratory protocol. Available vial sizes are 5 mg, 10 mg and 30 mg.

What did the weight-loss research show?

In the Phase 2 trial published in NEJM (2023), the highest-dose group had mean body-weight reduction of 24.2% at 48 weeks. These clinical findings are not claims for research vials or instructions for personal use.

Is this for human use?

No. Retatrutide is investigational and not approved for medical use. Products are strictly for laboratory research, not human consumption.

Buy Now — 10MG10 mg · $142.99 · Purple Peptides

Your next research purchase

Choose GLP3-R.
Source it from Purple Peptides.

5 mg, 10 mg or 30 mg. Find your research vial.

Buy Now at Purple Peptides10 mg · $142.99 · Purple Peptides
Lab tested & verified
Batch COA available
Fast fulfillment
U.S. based support

For research use only. Not for human consumption.